Dementia Subtypes

800 560 Joe Casciani PhD

Dementia is caused by various diseases and conditions, many with no cure. The table below shows the early symptoms, pathology, and prevalence of four main dementia subtypes, all progressive and irreversible.

Type of DementiaEarly SymptomsPathologyPrevalence
Alzheimer’s Diseaseimpaired memory, apathy, wandering, getting lost; problem recognizing others; impulsiveness; difficulty communicatingAbnormal deposits of amyloid plaques and tau tangles; slow, insidious decline50 to 70% of all irreversible dementias; onset >60, sometimes younger with family predisposition
Vascular DementiaMood fluctuations; some forgetting; difficulty following direction and new learning; misplacing itemsBlood clots disrupt blood flow, CV disease, single or multi-infarcts; stepwise decline20 to 30%; onset typically >65
Dementia with Lewy BodiesConcentration, attention and alertness; disorganized thinking, muscle rigidity, daytime sleepiness, loss of coordinationAbnormal deposits or aggregation of “lewy bodies” (alpha synuclein) affecting brain’s chemical signals<5%; onset at 50mor older (also seen in Parkinson’s disease)
Fronto-temporal DementiaDifficulty planning and organizing; personality and mood changes; difficulty with balance and walking, languageAbnormal amounts of tau and proteins in neurons in frontal and temporal lobes5 to 10%; typically younger onset (45-64)

Closing

This article on dementia subtypes is referenced in the Living to 100 Club’s new publication. It is Better, Longer & Happier: A Guide to Aging with Purpose and Positivity. In the Guide, Module 08 is focused entirely on gaining a better understanding of depression, dementia, and delirium.

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